Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting. • Identify how the P450 enzyme system plays a role in the body’s absorption, distribution, and clearance of medication. (first pass) • Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below. • Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map.